Case report<br>DRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin

Justyna Janocha-Litwin; Monika Pazgan-Simon; Krzysztof Simon

doi:10.5114/pdia.2014.40939

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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6/2014
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abstract:

Case report
DRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin

Justyna Janocha-Litwin

,

Monika Pazgan-Simon

,

Krzysztof Simon

Postep Derm Alergol 2014; XXXI, 6: 401–404

DOI: https://doi.org/10.5114/pdia.2014.40939

Online publish date: 2014/12/03

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AMA

Janocha-Litwin J, Pazgan-Simon M, Simon K. Case reportDRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2014;31(6):401-404. doi:10.5114/pdia.2014.40939.

APA

Janocha-Litwin, J., Pazgan-Simon, M.,  & Simon, K. (2014). Case reportDRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 31(6), 401-404. https://doi.org/10.5114/pdia.2014.40939

Chicago

Janocha-Litwin, Justyna, Monika Pazgan-Simon,  and Krzysztof Simon. 2014. "Case reportDRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 31 (6): 401-404. doi:10.5114/pdia.2014.40939.

Harvard

Janocha-Litwin, J., Pazgan-Simon, M.,  and Simon, K. (2014). Case reportDRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 31(6), pp.401-404. https://doi.org/10.5114/pdia.2014.40939

MLA

Janocha-Litwin, Justyna et al. "Case reportDRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 31, no. 6, 2014, pp. 401-404. doi:10.5114/pdia.2014.40939.

Vancouver

Janocha-Litwin J, Pazgan-Simon M, Simon K. Case reportDRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2014;31(6):401-404. doi:10.5114/pdia.2014.40939.

Various skin and systemic symptoms may develop as a complication of treatment with different medications and medicinal substances. One of them is a relatively rare drug reaction with eosinophilia and systemic symptoms, referred to as DRESS syndrome. The morphology of skin lesions and the patient’s general health can differ; the management involves withdrawal of drugs suspected of triggering DRESS syndrome, and administration of local and systemic glucocorticosteroids. In this paper we present a case of a patient with HCV associated chronic hepatitis, treated with peginterferon α2a (PEG-IFN-α2a) and ribavirin, who developed skin lesions and systemic symptoms typical of DRESS syndrome.

keywords:

Case reportDRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin

Justyna Janocha-Litwin , Monika Pazgan-Simon , Krzysztof Simon

DRESS syndrome, hepatitis C, interferon α, ribavirin

Case report
DRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin

Justyna Janocha-Litwin

,

Monika Pazgan-Simon

,

Krzysztof Simon