eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
6/2012
vol. 29
 
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abstract:

Case report
Ichthyosis as a paraneoplastic syndrome and atypical variant of mycosis fungoides: two cases report

Małgorzata Sokołowska-Wojdyło
,
Marta Malek
,
Hanna Majewska
,
Roman Nowicki
,
Jadwiga Roszkiewicz

Postep Derm Alergol 2012; XXIX, 6: 467-470
Online publish date: 2012/12/21
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Acquired ichthyosis is a known paraneoplastic sign of lymphoproliferative malignancies, but ichthyosiform eruption can also constitute a rare atypical variant of mycosis fungoides. Ichthyosiform mycosis fungoides differs from acquired ichthyosis associated with mycosis fungoides in histopathology. Histological pictures of paraneoplastic ichthyosis usually do not show any aspect related to malignancy in the skin. In both cases thinning of the granular layer and decrease of filaggrin in that layer are observed. We describe here 2 patients with mycosis fungoides, who were treated in the Department of Dermatology, the first one with ichthyosiform mycosis fungoides and the other one with acquired ichthyosis with coexisting mycosis fungoides.
keywords:

mycosis fungoides, ichthyosis, paraneoplastic syndrome

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