Case report<br>Pyoderma gangrenosum in a patient with common variable primary immunodeficiency

Beata Bergler-Czop; Ligia Brzezińska-Wcisło

doi:10.5114/pdia.2013.35622

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Case report
Pyoderma gangrenosum in a patient with common variable primary immunodeficiency

Beata Bergler-Czop

,

Ligia Brzezińska-Wcisło

Postep Derm Alergol 2013; XXX, 3: 188–191

DOI: https://doi.org/10.5114/pdia.2013.35622

Online publish date: 2013/06/20

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Pyoderma gangrenosum is a rare inflammatory skin condition that is associated with systemic inflammatory diseases. It is characterised by the presence of well-secluded, painful ulcerations, often located on the lower limbs. Similarly as in the case of acne inversa, patients’ markers of the inflammatory process are elevated; including OB,

C-reactive protein and leukocytosis. The aetiology takes into account an over-reactive inflammatory response to various factors (presence of the so-called pathergy symptom). Common variable primary immunodeficiency (CVID) is a disease that is rather often recognized and affects about 1/10,000-100,000 individuals. It is a heterogeneous group of disorders of combined B-and T-cell dysfunction. The case is described of a 22-year-old man with pyoderma gangrenosum that coexisted with CVID.

keywords:

Case reportPyoderma gangrenosum in a patient with common variable primary immunodeficiency

Beata Bergler-Czop , Ligia Brzezińska-Wcisło

pyoderma gangrenosum, immunodeficiency, inflammation

Case report
Pyoderma gangrenosum in a patient with common variable primary immunodeficiency

Beata Bergler-Czop

,

Ligia Brzezińska-Wcisło