eISSN: 2081-2841
ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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6/2017
vol. 9
 
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abstract:
Case report

Complete response in a patient with gynecological hidradenocarcinoma treated with exclusive external beam radiotherapy and brachytherapy: a case report

Flavio Giannelli
,
Ilaria Chiola
,
Liliana Belgioia
,
Stefania Garelli
,
Alice Pastorino
,
Michela Marcenaro
,
Serafina Mammoliti
,
Sergio Costantini
,
Nicolò Bizzarri
,
Valerio Vellone
,
Salvina Barra
,
Renzo Corvò

J Contemp Brachytherapy 2017; 9, 6: 572–578
DOI: https://doi.org/10.5114/jcb.2017.71554
Online publish date: 2017/12/30
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Hidradenocarcinoma (HC) is a very rare disease. This case report illustrates a successful treatment of a 60-year-old woman with vulvo-vaginal localization of hidradenocarcinoma treated with external beam radiotherapy delivered by helical tomotherapy with a simultaneous integrated boost (SIB), followed by brachytherapy. External beam radiotherapy dose prescription was 50.4 Gy in 28 fractions, five fractions per week to whole pelvis (planning target volume 1 – PTV1), 60.2 Gy in 28 fractions to SIB1 (fundus of uterus and right inguinal node), and 58.8 Gy in 28 fractions to SIB2 (lower/middle third of vagina, paraurethral region and right inguinal lymph nodes). Brachytherapy dose prescription was 28 Gy in 4 fractions for cervix, fundus of uterus and upper third of vagina (HR-CTV1), and 22 Gy in 4 fractions to middle third of vagina and paraurethral region (HR-CTV2). D90 for whole treatment was 91.9 Gy and 86.0 Gy for HR-CTV1 and HR-CTV2, respectively. Patient remained 12-months disease-free without treatment related side effects.
keywords:

high-dose-rate (HDR) brachytherapy, image-guide radiotherapy (IGRT), vulvo-vaginal hidradenocarcinoma

  
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