Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum

Yuko Kaneyasu; Iemasa Koh; Hisaya Fujiwara; Eiji Hirata; Yoshiki Kudo; Koji Arihiro; Norio Miharu; Tomio Nakagawa; Ippei Takahashi; Yuki Takeuchi; Nobuki Imano; Ikuno Nishibuchi; Takeo Nakashima; Daisuke Kawahara; Yoshimi Ohno; Yasushi Nagata

doi:10.5114/jcb.2019.84506

eISSN: 2081-2841
ISSN: 1689-832X

Journal of Contemporary Brachytherapy

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vol. 11

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abstract:

Case report

Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum

Yuko Kaneyasu

^{1, 2}

,

Iemasa Koh

³

,

Hisaya Fujiwara

⁴

,

Eiji Hirata

³

,

Yoshiki Kudo

³

,

Koji Arihiro

⁵

,

Norio Miharu

⁶

,

Tomio Nakagawa

¹

,

Ippei Takahashi

²

,

Yuki Takeuchi

²

,

Nobuki Imano

²

,

Ikuno Nishibuchi

²

,

Takeo Nakashima

⁷

,

Daisuke Kawahara

⁷

,

Yoshimi Ohno

⁷

,

Yasushi Nagata

²

Department of Radiation Oncology, National Hospital Organization Fukuyama Medical Center, Hiroshima, Japan
Department of Radiation Oncology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
Department of Obstetrics and Gynecology, Hiroshima University, Hiroshima, Japan
Department of Obstetrics and Gynecology, Japan Organization of Occupational Health and Safety, Chugoku Rosai Hospital, Hiroshima, Japan
Department of Anatomical Pathology, Hiroshima University Hospital, Hiroshima, Japan
Department of Obstetrics and Gynecology, Chuden Hospital, Hiroshima, Japan
Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, Hiroshima, Japan

J Contemp Brachytherapy 2019; 11, 2: 180–188

DOI: https://doi.org/10.5114/jcb.2019.84506

Online publish date: 2019/04/16

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AMA

Kaneyasu Y, Koh I, Fujiwara H, et al. Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum. Journal of Contemporary Brachytherapy. 2019;11(2):180-188. doi:10.5114/jcb.2019.84506.

APA

Kaneyasu, Y., Koh, I., Fujiwara, H., Hirata, E., Kudo, Y.,  & Arihiro, K. et al. (2019). Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum. Journal of Contemporary Brachytherapy, 11(2), 180-188. https://doi.org/10.5114/jcb.2019.84506

Chicago

Kaneyasu, Yuko, Iemasa Koh, Hisaya Fujiwara, Eiji Hirata, Yoshiki Kudo, Koji Arihiro,  and Norio Miharu et al. 2019. "Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum". Journal of Contemporary Brachytherapy 11 (2): 180-188. doi:10.5114/jcb.2019.84506.

Harvard

Kaneyasu, Y., Koh, I., Fujiwara, H., Hirata, E., Kudo, Y., Arihiro, K., Miharu, N., Nakagawa, T., Takahashi, I., Takeuchi, Y., Imano, N., Nishibuchi, I., Nakashima, T., Kawahara, D., Ohno, Y.,  and Nagata, Y. (2019). Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum. Journal of Contemporary Brachytherapy, 11(2), pp.180-188. https://doi.org/10.5114/jcb.2019.84506

MLA

Kaneyasu, Yuko et al. "Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum." Journal of Contemporary Brachytherapy, vol. 11, no. 2, 2019, pp. 180-188. doi:10.5114/jcb.2019.84506.

Vancouver

Kaneyasu Y, Koh I, Fujiwara H, Hirata E, Kudo Y, Arihiro K et al. Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum. Journal of Contemporary Brachytherapy. 2019;11(2):180-188. doi:10.5114/jcb.2019.84506.

In November 2011, a 61-year-old woman was diagnosed with squamous cell carcinoma (SCC) of the cervix in a uterus didelphys with vaginal septum. The patient was diagnosed with Fédération Internationale de Gynécologie et d’Obstétrique (FIGO) stage IIB because of infiltration to the left parametrium without infiltration to the pelvic wall. The patient was treated with external-beam radiotherapy (EBRT) and brachytherapy (BT), using concomitant chemotherapy with cisplatin. A total of 50 Gy were delivered (2 Gy/fraction/day) to the pelvis, with a central shield after 40 Gy. The patient was treated four times with BT (6 Gy × 4 fractions), with tandem and ovoid applicators inserted once to the left side; tandem to the left side and ovoid bilaterally were inserted twice; and tandem to the right side and ovoid bilaterally were inserted once. Six years and 8 months after the start of treatment, the patient had had no relapse or severe late adverse effects. For accurate diagnosis and optimal treatment of the uterus didelphys, careful interview and pelvic examination at initial diagnosis of a patient are very important.

keywords:

Concurrent chemoradiotherapy for locally advanced squamous cell carcinoma of the cervix in a uterus didelphys with vaginal septum

Yuko Kaneyasu 1, 2 , Iemasa Koh 3 , Hisaya Fujiwara 4 , Eiji Hirata 3 , Yoshiki Kudo 3 , Koji Arihiro 5 , Norio Miharu 6 , Tomio Nakagawa 1 , Ippei Takahashi 2 , Yuki Takeuchi 2 , Nobuki Imano 2 , Ikuno Nishibuchi 2 , Takeo Nakashima 7 , Daisuke Kawahara 7 , Yoshimi Ohno 7 , Yasushi Nagata 2

cervical cancer, brachytherapy, uterus didelphys, vaginal septum, concurrent chemoradiotherapy