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ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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3/2024
vol. 16
 
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abstract:
Original paper

Dosimetric comparison between single-channel vaginal cylinder and free-hand interstitial needles in vaginal brachytherapy of gynecological cancers

Kaiqiang Chen
1
,
Yanhong Zhuo
2
,
Zirong Li
3
,
Penggang Bai
1
,
Jihong Chen
1
,
Yibin Lin
1
,
Jing Liu
1
,
Li Li
1
,
Yang Yang
1
,
Junping Pan
1
,
Yanwen Song
1
,
Tianming Wu
4
,
Xiuchun Zhang
1
,
Qin Xu
1

  1. Fujian Provincial Cancer Hospital, Jinan District, Fujian Province Fuzhou, 350014 Fuzhou City, China
  2. Zhangzhou Municipal Hospital of Fujian Province and Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
  3. Longyan First Hospital, Xinluo District, 364000, Longyan City, China
  4. University of Chicago Medicine, Chicago, IL 60637, USA
J Contemp Brachytherapy 2024; 16, 3: 219–224
DOI: https://doi.org/10.5114/jcb.2024.141169
Online publish date: 2024/06/28
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Purpose:
To compare the dosimetric differences in vaginal brachytherapy (VBT) using single-channel vaginal cylinder (SCVC) and free-hand interstitial needles (FIN).

Material and methods:
Twenty-two women with malignant gynecologic tumors were prospectively treated with image-guided high-dose-rate (HDR) brachytherapy after surgery and external beam radiation therapy (EBRT). All HDR treatments were delivered using FIN implant technique. For dosimetric comparison purposes only, SCVCs of 2.5 cm diameter were placed in all patients. No sources were dwelled in cylinder applicator during clinical treatment. CT-guided brachytherapy treatment planning was performed according to GEC-ESTRO guidelines, with high-risk clinical target volume (HR-CTV) delineated based on clinical exams and MRI T2 sequences. Dose-volume parameters to HR-CTV and surrounding organs at risk (OARs) from interstitial plans were compared with those achieved from cylinder plans.

Results:
Compared with SCVC group, FIN group showed the same HR-CTV coverage. FIN group had higher V150% and V200% (p < 0.05). In addition, it had lower HI (p < 0.05). However, doses to the rectum D0.1cc (538.5 ±119.8 cGy), D1cc (415.4 ±73.3 cGy), D2cc (355.7 ±66.6 cGy), and Dmean (162.8 ±43.7 cGy) as well as the bladder D0.1cc (516.1 ±85.2 cGy) and D1cc (392.9 ±59.8 cGy) were lower in FIN group than in SCVC group (p < 0.05).

Conclusions:
FIN technique can be a dosimetrically preferable alternative to the commonly used SCVC for HDR VBT boost in patients with gynecological malignancies. It provides adequate coverage of target volumes, with minimal radiation dose to surrounding organs at risk.

keywords:

free-hand, interstitial brachytherapy, vaginal cylinder, vaginal brachytherapy

  
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