Image-guided interstitial brachytherapy boost for nasopharyngeal carcinoma: technical aspects

Naoya Murakami; Guanghui Cheng; Seiichi Yoshimoto; Jun Itami

doi:10.5114/jcb.2020.96874

eISSN: 2081-2841
ISSN: 1689-832X

Journal of Contemporary Brachytherapy

Current Issue Archive Supplements Articles in Press Journal Information Aims and Scope Editorial Office Editorial Board Register as Author Register as Reviewer Instructions for Authors Abstracting and indexing Subscription Advertising Information Links

Editorial System

Submit your Manuscript

3/2020
vol. 12

Send email

Copy url:

abstract:

Original paper

Image-guided interstitial brachytherapy boost for nasopharyngeal carcinoma: technical aspects

Naoya Murakami

¹

,

Guanghui Cheng

²

,

Seiichi Yoshimoto

³

,

Jun Itami

¹

Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan
Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China
Department of Head and Neck Surgery, National Cancer Center Hospital, Japan

J Contemp Brachytherapy 2020; 12, 3: 294–302

DOI: https://doi.org/10.5114/jcb.2020.96874

Online publish date: 2020/06/30

View full text Get citation

Nasopharyngeal cancer generally responds well to concurrent chemoradiotherapy (CCRT). However, there is a small group of patients who respond poorly to CCRT, and experience local residual tumor or local relapse. Although several attempts have been performed to such a group of patients including re-irradiation with external beam radiation therapy (EBRT) or salvage surgery, clinical results remain unsatisfactory. Intracavitary brachytherapy (ICBT) boost after CCRT with EBRT has been explored, however, its efficacy is limited to those with superficial residual tumors. For those residual tumors thickness with more than 5 mm, interstitial brachytherapy (ISBT) boost would be an appropriate modality of choice.

Here, we describe technical aspects of the high-dose-rate interstitial brachytherapy (HDR-ISBT) boost for nasopharyngeal cancer (NPC) patients who responded poorly to the CCRT with EBRT.

keywords:

Image-guided interstitial brachytherapy boost for nasopharyngeal carcinoma: technical aspects

Naoya Murakami 1 , Guanghui Cheng 2 , Seiichi Yoshimoto 3 , Jun Itami 1

nasopharyngeal carcinoma, interstitial brachytherapy boost, image-guided brachytherapy

Naoya Murakami

¹

,

Guanghui Cheng

²

,

Seiichi Yoshimoto

³

,

Jun Itami

¹