Invited review<br>Hypertension and obstructive sleep apnoea

Jacek Wolf; Krzysztof Narkiewicz

ISSN: 1734-1922

Archives of Medical Science Special Issues

Current issue Archive Archives of Medical Science

2/2009

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abstract:

Invited review
Hypertension and obstructive sleep apnoea

Jacek Wolf

,

Krzysztof Narkiewicz

Arch Med Sci 2009; 5, 2A: S 330–S 336

Online publish date: 2009/08/04

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Several epidemiological and experimental studies have demonstrated a close relationship between sleep-disordered breathing and cardiovascular disease. Obstructive sleep apnoea has been linked to hypertension in a dose-dependant and time-related manner. Postulated underlying mechanisms involve autonomic nervous system alterations, chemoreceptor and baroreceptor responsiveness impairment, higher levels of vasoactive hormones and impaired endothelial function. Continuous positive airway pressure (CPAP) therapy for obstructive sleep apnoea may significantly improve blood pressure control and influence target organ damage, previously ascribed to hypertension alone.

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Invited reviewHypertension and obstructive sleep apnoea

Jacek Wolf , Krzysztof Narkiewicz

obstructive sleep apnoea, hypertension, continuous positive airway pressure therapy

Invited review
Hypertension and obstructive sleep apnoea

Jacek Wolf

,

Krzysztof Narkiewicz