eISSN: 1731-2531
ISSN: 1642-5758
Anaesthesiology Intensive Therapy
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Reviewers Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search

Open access

without publication fees

Journal integrated with

integrated with publons
5/2021
vol. 53
 
Share:
Send email
Share:
abstract:
Original paper

Non-invasive mechanical ventilation with average volume-assured pressure support. Results according to the aetiology of acute respiratory failure

Killen Harold Briones Claudett
1, 2
,
Antonio Esquinas Rodriguez
3
,
Mónica H. Briones Claudett
2, 4
,
Miguel Puga Tejada
2
,
Mariuxi del Pilar Cabrera Bańos
5
,
Jorge Daher N.
1
,
Byron Bermeo
6
,
Michelle Grunauer
7

  1. Faculty of Medical Sciences, University of Guayaquil, Guayaquil, Ecuador
  2. Physiological-Respiratory Center, Briones-Claudett, Guayaquil, Ecuador
  3. Intensive Care Unit, Morales Masaguer, Murcia, Spain
  4. Intensive Care Unit, Ecuadorian Institute of Social Security (IESS), Babahoyo, Ecuador
  5. Intensive Care Unit, Santa Maria Clinic, Guayaquil, Ecuador
  6. National Thorax Institute, Santiago de Chile, Chile
  7. School of Medicine, Universidad San Francisco de Quito, Quito, Ecuador
Anaesthesiol Intensive Ther 2021; 53, 5: 403–410
DOI: https://doi.org/10.5114/ait.2021.111527
Online publish date: 2021/12/30
View full text Get citation
 
PlumX metrics:
Introduction
Until now, the ventilatory strategy with BiPAP S/T plus average volume-assured pressure support (AVAPS) has not been evaluated for its use in the different types of acute respiratory failure (ARF). Consequently we report the results of the use of this ventilatory strategy in these clinical scenarios.

Material and methods
This is a single-centre prospective study. The subjects were categorised according to the type of ARF: (1) hypercapnic ARF: chronic obstructive pulmonary disease and bronchial asthma; and (2) hypoxaemic ARF: pneumonia, acute respiratory distress syndrome, congestive heart failure, and interstitial lung disease. Multiple logistic regression was used to determine predictors of non-invasive mechanical ventilation (NIV) failure (intubation). Further, in a subgroup of patients with de novo hypoxaemic ARF, analysis of variances with repeated measures was used to determine factors associated with NIV outcome.

Results
Sixty-eight subjects were included in this study. The NIV success rate was 69.1% and the mortality rate was 20.6%. A multivariate analysis showed that the number of affected lung quadrants on chest X-ray (OR: 4.23, 95% CI: 4.17–4.31; P < 0.001) and ARF precipitating disease (OR: 4.46, 95% CI: 4.43–4.51; P < 0.001) were determinants of NIV failure. In the hypoxaemic ARF subgroup (n = 58), significant differences in several parameters were found between patients with positive and negative outcomes.

Conclusions
The use of BiPAP S/T – AVAPS in subjects with hypercapnic ARF is associated with a better outcome than in those with de novo hypoxaemic ARF.

keywords:

non-invasive mechanic ventilation, volume-guaranteed ventilation, acute respiratory failure, chronic obstructive pulmonary disease, hypercapnic acute respiratory failure
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.