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ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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5/2022
vol. 39
 
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abstract:
Original paper

Optical rhinometry in assessing the nasal mucosa reaction during nasal allergen provocation testing

Edyta Krzych-Fałta
1
,
Konrad Furmańczyk
2
,
Khrystyna Lishchuk-Yakymovych
3
,
Piotr Samel-Kowalik
4
,
Oksana Wojas
4
,
Adam Sybilski
5

  1. Nursing Basics Facility, Medical University of Warsaw, Warsaw, Poland
  2. Institute of Technical Information Technology, Faculty of Applied Mathematics, Warsaw University of Life Sciences, Warsaw, Poland
  3. Department of Immunology and Allergy, Lviv National Medical University, Lviv, Ukraine
  4. Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
  5. Second Department of Paediatrics, Medical Centre for Postgraduate Education, Warsaw, Poland
Adv Dermatol Allergol 2022; XXXIX (5): 902-907
DOI: https://doi.org/10.5114/ada.2021.112459
Online publish date: 2022/01/09
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Introduction
Optical rhinometry is a newly standardized technique for assessing nasal obstruction in nasal allergen provocation testing. It is one of the few techniques that accurately determine the beginning of an allergic reaction as it measures optical density, which is consistent with the degree of response.

Aim: To evaluate the usefulness of optical rhinometry in nasal allergen provocation testing.

Material and methods
The study population was a group of 45 subjects (25 diagnosed with an allergy to common environmental allergens and 20 controls). Nasal allergen provocation testing was conducted with the use of Dermatophagoides pteronyssinus and Dermatophagoides farina (5,000 SBU/ml).

Results
The onset of the nasal mucosa allergen response in the form of nasal obstruction was observed at 10.40 min. The subsequent reaction developed rapidly, with only 53 s from the initial stage of nasal obstruction to complete obstruction (optical density 0.4552).

Conclusions
Due to its informative potential, optical rhinometry is a valuable tool in assessing the nasal mucosal response to topical allergen application.

keywords:

optical rhinometry, nasal allergen provocation testing
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