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ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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1/2014
vol. 6
 
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abstract:

Original paper
High-dose-rate interstitial brachytherapy for mobile tongue cancer: preliminary results of a dose reduction trial

Hironori Akiyama
,
Ken Yoshida
,
Hideya Yamazaki
,
Tadashi Takenaka
,
Tadayuki Kotsuma
,
Koji Masui
,
Yasuo Yoshioka
,
Takumi Arika
,
Kimishige Shimizutani
,
Eiichi Tanaka

J Contemp Brachytherapy 2014; 6, 1: 10–14
DOI: https://doi.org/10.5114/jcb.2014.40726
Online publish date: 2014/02/19
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Purpose: To compare the outcome of our facility with another about the shortened schedule (60 Gy in 10 fractions to 54 Gy in 9 fractions) of high-dose-rate interstitial brachytherapy (HDR ISBT) for mobile tongue cancer.

Material and methods: Eighteen patients were treated with HDR ISBT as a monotherapy in dose reduction schedule with some unique technique to determine the border of tumor accuracy (lugol’s staining and metal marker), and to minimize adverse effect (lead-lined silicon block) at our facility.

Results: The 2-year local and regional control rates and cause-specific survival rate were 82%, 80%, and 83% and moderate to severe late complications occurred in five patients (28%), which were almost the same treatment results achieved by another facility.

Conclusions: We recommend 54 Gy in 9 fractions over 7 days as a feasible treatment to reduce patient discomfort in mobile tongue cancer patients.
keywords:

dose reduction, high-dose-rate brachytherapy, tongue cancer

  
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