Original paper<br>The use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department

Cristina Gutiérrez; Dina Najjari; Evelyn Martínez; Saray Botella; Arantxa Eraso; Francisco Pino; Ferran Moreno; Joan Pera; Ferran Guedea

doi:10.5114/jcb.2014.46757

eISSN: 2081-2841
ISSN: 1689-832X

Journal of Contemporary Brachytherapy

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Original paper
The use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department

Cristina Gutiérrez

,

Dina Najjari

,

Evelyn Martínez

,

Saray Botella

,

Arantxa Eraso

,

Francisco Pino

,

Ferran Moreno

,

Joan Pera

,

Ferran Guedea

J Contemp Brachytherapy 2014; 6, 4: 397–403

DOI: https://doi.org/10.5114/jcb.2014.46757

Online publish date: 2014/11/17

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AMA

Gutiérrez C, Najjari D, Martínez E, et al. Original paperThe use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department. Journal of Contemporary Brachytherapy. 2014;6(4):397-403. doi:10.5114/jcb.2014.46757.

APA

Gutiérrez, C., Najjari, D., Martínez, E., Botella, S., Eraso, A.,  & Pino, F. et al. (2014). Original paperThe use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department. Journal of Contemporary Brachytherapy, 6(4), 397-403. https://doi.org/10.5114/jcb.2014.46757

Chicago

Gutiérrez, Cristina, Dina Najjari, Evelyn Martínez, Saray Botella, Arantxa Eraso, Francisco Pino,  and Ferran Moreno et al. 2014. "Original paperThe use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department". Journal of Contemporary Brachytherapy 6 (4): 397-403. doi:10.5114/jcb.2014.46757.

Harvard

Gutiérrez, C., Najjari, D., Martínez, E., Botella, S., Eraso, A., Pino, F., Moreno, F., Pera, J.,  and Guedea, F. (2014). Original paperThe use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department. Journal of Contemporary Brachytherapy, 6(4), pp.397-403. https://doi.org/10.5114/jcb.2014.46757

MLA

Gutiérrez, Cristina et al. "Original paperThe use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department." Journal of Contemporary Brachytherapy, vol. 6, no. 4, 2014, pp. 397-403. doi:10.5114/jcb.2014.46757.

Vancouver

Gutiérrez C, Najjari D, Martínez E, Botella S, Eraso A, Pino F et al. Original paperThe use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department. Journal of Contemporary Brachytherapy. 2014;6(4):397-403. doi:10.5114/jcb.2014.46757.

Purpose: To demonstrate the utility of a boost with interstitial brachytherapy (BT) in breast-conserving therapy (BCT) by doing a thorough review of the literature and describing in detail our technique for delivering this boost.

Material and methods: Our department has been delivering the boost with interstitial BT since 1989, in most cases with rigid needles and a theoretical dosimetry. In the early years, we used low-dose-rate (LDR) with iridium-192 wires. The dose administered was 15 Gy if there were no risk factors for local relapse or 20-25 Gy in the presence of risk factors. The risk factors considered were the presence of a close margin (less than 10 mm) and an extensive intraductal component (more than 25%). After 2002, we switched to high-dose-rate (HDR); using the linear quadratic model we changed the low dose to 3 fractions of 4.5 Gy in the case of no risk factors for local relapse or to 3 fractions of 5 Gy in the presence of risk factors.

Results: In 79 consecutive boost patients treated in our department between 2010 and 2011, with a median follow-up of 46 months, the local control rate was 97.47%. With respect to cosmesis, fibrosis occurred in 17 cases (21.5%) and hyperpigmentation in 26 cases (32.9%). Our hospital’s results are comparable in terms of local control and cosmesis to those of other authors.

Conclusions: This educational article describes our department’s boost technique with rigid needles and comments briefly on our results using this technique in a group of consecutively treated patients in our department. A review of the literature and the published results on local control and cosmesis is also described.

keywords:

Original paperThe use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department

Cristina Gutiérrez , Dina Najjari , Evelyn Martínez , Saray Botella , Arantxa Eraso , Francisco Pino , Ferran Moreno , Joan Pera , Ferran Guedea

brachytherapy, breast cancer, breast conserving therapy, interstitial boost

Original paper
The use of an interstitial boost in the conservative treatment of breast cancer: how to perform it routinely in a radiotherapy department

Cristina Gutiérrez

,

Dina Najjari

,

Evelyn Martínez

,

Saray Botella

,

Arantxa Eraso

,

Francisco Pino

,

Ferran Moreno

,

Joan Pera

,

Ferran Guedea