Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap

Emily Flower; Kathy Ngoc Tran; Salman Zanjani; Wayne Smith; Jonathan Karpelowsky; Katie Summerhayes; Edgar Estoesta; Jennifer Chard

doi:10.5114/jcb.2016.62962

eISSN: 2081-2841
ISSN: 1689-832X

Journal of Contemporary Brachytherapy

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abstract:

Case report

Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap

Emily Flower

,

Kathy Ngoc Tran

,

Salman Zanjani

,

Wayne Smith

,

Jonathan Karpelowsky

,

Katie Summerhayes

,

Edgar Estoesta

,

Jennifer Chard

J Contemp Brachytherapy 2016; 8, 5: 429–433

DOI: https://doi.org/10.5114/jcb.2016.62962

Online publish date: 2016/10/11

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AMA

Flower E, Tran K, Zanjani S, et al. Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap. Journal of Contemporary Brachytherapy. 2016;8(5):429-433. doi:10.5114/jcb.2016.62962.

APA

Flower, E., Tran, K., Zanjani, S., Smith, W., Karpelowsky, J.,  & Summerhayes, K. et al. (2016). Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap. Journal of Contemporary Brachytherapy, 8(5), 429-433. https://doi.org/10.5114/jcb.2016.62962

Chicago

Flower, Emily, Kathy Ngoc Tran, Salman Zanjani, Wayne Smith, Jonathan Karpelowsky, Katie Summerhayes,  and Edgar Estoesta et al. 2016. "Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap". Journal of Contemporary Brachytherapy 8 (5): 429-433. doi:10.5114/jcb.2016.62962.

Harvard

Flower, E., Tran, K., Zanjani, S., Smith, W., Karpelowsky, J., Summerhayes, K., Estoesta, E.,  and Chard, J. (2016). Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap. Journal of Contemporary Brachytherapy, 8(5), pp.429-433. https://doi.org/10.5114/jcb.2016.62962

MLA

Flower, Emily et al. "Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap." Journal of Contemporary Brachytherapy, vol. 8, no. 5, 2016, pp. 429-433. doi:10.5114/jcb.2016.62962.

Vancouver

Flower E, Tran K, Zanjani S, Smith W, Karpelowsky J, Summerhayes K et al. Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap. Journal of Contemporary Brachytherapy. 2016;8(5):429-433. doi:10.5114/jcb.2016.62962.

Purpose: To report peri-operative fractionated high-dose-rate (HDR) brachytherapy with a 3D customized Freiburg flap applicator to treat locally recurrent Wilms’ tumor, followed by immediate hyperthermic intraperitoneal chemotherapy for a 16-year-old with a second recurrence of nephroblastoma (Wilms’ tumor).

Material and methods: The tumor was excised and surgical bed was treated with fractionated HDR brachytherapy using a Freiburg flap applicator. Hyperthermic intraperitoneal chemotherapy was performed immediately after the removal of brachytherapy applicator.

Results: The Freiburg flap was successfully reconstructed to enable delivery of conformable peri-operative HDR brachytherapy. The clinical target volume (CTV) D90 was 26 Gy in 5 fractions.

Conclusions: Peri-operative fractionated HDR brachytherapy with a customized Freiburg flap applicator was delivered successfully across a large multi-disciplinary team.

keywords:

Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms’ tumor using a reconstructed Freiburg flap

Emily Flower , Kathy Ngoc Tran , Salman Zanjani , Wayne Smith , Jonathan Karpelowsky , Katie Summerhayes , Edgar Estoesta , Jennifer Chard

nephroblastoma, pediatric brachytherapy, peri-operative, Wilms tumor

Emily Flower

,

Kathy Ngoc Tran

,

Salman Zanjani

,

Wayne Smith

,

Jonathan Karpelowsky

,

Katie Summerhayes

,

Edgar Estoesta

,

Jennifer Chard