Perioperative thromboembolism prophylaxis in children – is it necessary?

Izabela Pągowska-Klimek

doi:10.5114/ait.2020.97599

eISSN: 1731-2531
ISSN: 1642-5758

Anaesthesiology Intensive Therapy

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abstract:

Review paper

Perioperative thromboembolism prophylaxis in children – is it necessary?

Izabela Pągowska-Klimek

¹

Department of Paediatric Anaesthesiology and Intensive Care, Warsaw Medical University, Warsaw, Poland

Anaesthesiol Intensive Ther 2020; 52, 4: 316–322

DOI: https://doi.org/10.5114/ait.2020.97599

Online publish date: 2020/08/06

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Perioperative antithrombotic prophylaxis in adults is widely recommended. In the past, it was believed that this does not concern the paediatric population. Recently, however, there has been growing evidence that the incidence of venous thromboembolism (VTE) in children is increasing and is probably underestimated. This is a result of advances in treatment of previously lethal conditions, wide use of central venous catheters, and improved awareness and diagnosis of VTE complications. However, large clinical trials assessing the efficacy and safety of antithrombotic treatment in children have not been conducted and there are not widely accepted protocols of perioperative prophylaxis. At the same time, there is a growing awareness of its sequelae: compartment syndrome, pulmonary embolism, pulmonary hypertension, post-thrombotic syndrome, cost, length of hospital stay, and mortality. Local recommendations based on observational studies, individual experience, and extrapolation from data of adults have emerged.

keywords:

Perioperative thromboembolism prophylaxis in children – is it necessary?

Izabela Pągowska-Klimek 1

venous thromboembolism, paediatric surgery, thromboembolism prophylaxis, perioperative thromboembolism

Izabela Pągowska-Klimek

¹