Quality of life in infants with atopic dermatitis
and their families

Milena Ražnatović Djurović; Janko Janković; Anda Cirkovic; Vesna Tomic Spiric; Natasa Maksimovic; Zorica Sojevic Timotijevic; Danica Vukićević; Zlatica Mirkovic; Leonida Vitkovic; Slavenka Janković

doi:10.5114/ada.2020.93385

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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Original paper

Quality of life in infants with atopic dermatitis and their families

Milena Ražnatović Djurović

¹

,

Janko Janković

²

,

Anda Cirkovic

³

,

Vesna Tomic Spiric

^{4, 5}

,

Natasa Maksimovic

⁶

,

Zorica Sojevic Timotijevic

⁷

,

Danica Vukićević

⁸

,

Zlatica Mirkovic

⁹

,

Leonida Vitkovic

¹⁰

,

Slavenka Janković

⁶

Clinic of Dermatology and Venereology, Clinical Centre of Montenegro, Faculty of Medicine, University of Montenegro, Podgorica, Montenegro
Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
nstitute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Clinic for Allergology and Immunology, Clinical Centre of Serbia, Belgrade, Serbia
Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Department of Dermatology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia
Institute of Pathology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia
Department of Internal Medicine, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia
Institute of Histology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia

Adv Dermatol Allergol 2020; XXXVII (1): 66-72

DOI: https://doi.org/10.5114/ada.2020.93385

Online publish date: 2020/03/09

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AMA

Ražnatović Djurović M, Janković J, Cirkovic A, et al. Quality of life in infants with atopic dermatitis
and their families. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2020;37(1):66-72. doi:10.5114/ada.2020.93385.

APA

Ražnatović Djurović, M., Janković, J., Cirkovic, A., Tomic Spiric, V., Maksimovic, N.,  & Sojevic Timotijevic, Z. et al. (2020). Quality of life in infants with atopic dermatitis
and their families. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 37(1), 66-72. https://doi.org/10.5114/ada.2020.93385

Chicago

Ražnatović Djurović, Milena, Janko Janković, Anda Cirkovic, Vesna Tomic Spiric, Natasa Maksimovic, Zorica Sojevic Timotijevic,  and Danica Vukićević et al. 2020. "Quality of life in infants with atopic dermatitis
and their families". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 37 (1): 66-72. doi:10.5114/ada.2020.93385.

Harvard

Ražnatović Djurović, M., Janković, J., Cirkovic, A., Tomic Spiric, V., Maksimovic, N., Sojevic Timotijevic, Z., Vukićević, D., Mirkovic, Z., Vitkovic, L.,  and Janković, S. (2020). Quality of life in infants with atopic dermatitis
and their families. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 37(1), pp.66-72. https://doi.org/10.5114/ada.2020.93385

MLA

Ražnatović Djurović, Milena et al. "Quality of life in infants with atopic dermatitis
and their families." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 37, no. 1, 2020, pp. 66-72. doi:10.5114/ada.2020.93385.

Vancouver

Ražnatović Djurović M, Janković J, Cirkovic A, Tomic Spiric V, Maksimovic N, Sojevic Timotijevic Z et al. Quality of life in infants with atopic dermatitis
and their families. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2020;37(1):66-72. doi:10.5114/ada.2020.93385.

Introduction
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease, with a significant effect on quality of life (QoL).

Aim
To evaluate the impact of AD on QoL of Montenegrin infants and their parents and to identify predictors affecting their QoL.

Material and methods
The cross-sectional study was conducted between August 2017 and July 2018 and included 186 infants with AD aged 0–4 years and their parents. The severity of disease was measured by the Three-Item Severity (TIS) score, while QoL was assessed with the Infants’ Dermatitis Quality of Life Index (IDQOL) and the Dermatitis Family Impact (DFI) questionnaire.

Results
The mean overall scores were 14.72 for IDQOL and 17.78 for DFI. The positive correlation was observed between AD severity and both the IDQOL and DFI scores (r = 0.61, p < 0.001 and r = 0.67, p < 0.001, respectively). The highest-scoring IDQOL items were “itching and scratching”, and “child’s mood”. Poorer infants’ QoL was associated with more serious AD (B = 2.56; 95% confidence interval (CI): 2.08–3.04), concomitant atopic disease (B = 3.86; 95% CI: 1.78–5.94), family history of atopic disease (B = 3.80; 95% CI: 1.84–5.77), older age of the child (B = 1.14; 95% CI: 0.20–2.07) and older age of the parent (B = 0.28; 95% CI: 0.04–0.53). Similarly, parents had poorer QoL if their infants had more severe AD (B = 2.56; 95% CI: 2.14–2.87), another atopic disease (B = 2.91; 95% CI: 0.99–4.84) or family history of atopic disease (B = 4.33; 95% CI: 2.57–6.09).

Conclusions
Our results demonstrate that AD has a significant negative impact on infants’ QoL as well as on QoL of their parents.

keywords:

Quality of life in infants with atopic dermatitis and their families

Milena Ražnatović Djurović 1 , Janko Janković 2 , Anda Cirkovic 3 , Vesna Tomic Spiric 4, 5 , Natasa Maksimovic 6 , Zorica Sojevic Timotijevic 7 , Danica Vukićević 8 , Zlatica Mirkovic 9 , Leonida Vitkovic 10 , Slavenka Janković 6

atopic dermatitis, quality of life, Infants’ Dermatitis Quality of Life Index, Dermatitis Family Impact, infants, family impact, Montenegro

Milena Ražnatović Djurović

¹

,

Janko Janković

²

,

Anda Cirkovic

³

,

Vesna Tomic Spiric

^{4, 5}

,

Natasa Maksimovic

⁶

,

Zorica Sojevic Timotijevic

⁷

,

Danica Vukićević

⁸

,

Zlatica Mirkovic

⁹

,

Leonida Vitkovic

¹⁰

,

Slavenka Janković

⁶