Review paper<br>Acitretin in psoriasis treatment – recommended treatment regimens

Marta Pastuszka; Andrzej Kaszuba

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

2/2012
vol. 29

Send email

Copy url:

abstract:

Review paper
Acitretin in psoriasis treatment – recommended treatment regimens

Marta Pastuszka

,

Andrzej Kaszuba

Post Dermatol Alergol 2012; XXIX, 2: 94–103
[Polish version: Post Dermatol Alergol 2012; XXIX, 2: 104-113]

Online publish date: 2012/04/24

View full text Get citation

Acitretin is a synthetic retinoid, a pharmacologically active metabolite of etretinate. It is characterized by very favourable pharmacological profile: its period of half-life is approximately 2 days, it is nearly 50 times less lipophilic than etretinate, and its efficacy in the treatment of psoriasis is comparable to etretinate. The mechanism of its action is not yet fully understood, but it is known that acitretin normalizes all processes typical for psoriasis.

The paper discusses in details the indications for acitretin, its efficacy in monotherapy and combination therapy, the principles of alternate therapy, and also the most common side effects during treatment. In addition, we classify the most important recommendations to be aware of before, during and after treatment.

keywords:

Review paperAcitretin in psoriasis treatment – recommended treatment regimens

Marta Pastuszka , Andrzej Kaszuba

acitretin, psoriasis, efficacy, combination therapy, alternate therapy

Review paper
Acitretin in psoriasis treatment – recommended treatment regimens

Marta Pastuszka

,

Andrzej Kaszuba