Review paper<br>Chemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis

Bogusław Nedoszytko; Małgorzata Sokołowska-Wojdyło; Katarzyna Ruckemann-Dziurdzińska; Jadwiga Roszkiewicz; Roman Nowicki

doi:10.5114/pdia.2014.40920

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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2/2014
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Review paper
Chemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis

Bogusław Nedoszytko

,

Małgorzata Sokołowska-Wojdyło

,

Katarzyna Ruckemann-Dziurdzińska

,

Jadwiga Roszkiewicz

,

Roman J. Nowicki

Postep Derm Alergol 2014; XXXI, 2: 84–91

DOI: https://doi.org/10.5114/pdia.2014.40920

Online publish date: 2014/04/22

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AMA

Nedoszytko B, Sokołowska-Wojdyło M, Ruckemann-Dziurdzińska K, Roszkiewicz J, Nowicki RJ. Review paperChemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2014;31(2):84-91. doi:10.5114/pdia.2014.40920.

APA

Nedoszytko, B., Sokołowska-Wojdyło, M., Ruckemann-Dziurdzińska, K., Roszkiewicz, J.,  & Nowicki, R. J. (2014). Review paperChemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 31(2), 84-91. https://doi.org/10.5114/pdia.2014.40920

Chicago

Nedoszytko, Bogusław, Małgorzata Sokołowska-Wojdyło, Katarzyna Ruckemann-Dziurdzińska, Jadwiga Roszkiewicz,  and Roman J Nowicki. 2014. "Review paperChemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 31 (2): 84-91. doi:10.5114/pdia.2014.40920.

Harvard

Nedoszytko, B., Sokołowska-Wojdyło, M., Ruckemann-Dziurdzińska, K., Roszkiewicz, J.,  and Nowicki, R. (2014). Review paperChemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 31(2), pp.84-91. https://doi.org/10.5114/pdia.2014.40920

MLA

Nedoszytko, Bogusław et al. "Review paperChemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 31, no. 2, 2014, pp. 84-91. doi:10.5114/pdia.2014.40920.

Vancouver

Nedoszytko B, Sokołowska-Wojdyło M, Ruckemann-Dziurdzińska K, Roszkiewicz J, Nowicki R. Review paperChemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2014;31(2):84-91. doi:10.5114/pdia.2014.40920.

Chemokines are signaling peptides which regulate cell trafficking and provide control of the tissue-specific cell homing. In the skin, chemokines are secreted both by the resident cells such as keratinocytes, melanocytes, fibroblasts, dendritic cells and mast cells, as well as by infiltrated cells – lymphocytes, eosinophils, and monocytes. Chemokines, together with cytokines, participate in induction and maintenance of inflammation in the skin and regulate the composition of the cellular infiltrates. Inflammation within the skin is a feature shared by atopic dermatitis and psoriasis, two of the most common dermatoses. Accumulation of activated mast cells in the affected skin is seen both in atopic dermatitis and in psoriasis. This paper presents a concise overview of the current knowledge on the role chemokines have in pathogenesis of atopic dermatitis, psoriasis, and mastocytosis, a disease caused directly by the accumulation and activation of mast cells in the skin.

keywords:

Review paperChemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis

Bogusław Nedoszytko , Małgorzata Sokołowska-Wojdyło , Katarzyna Ruckemann-Dziurdzińska , Jadwiga Roszkiewicz , Roman J. Nowicki

chemokine, cytokines, atopic dermatitis, psoriasis, mastocytosis

Review paper
Chemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis

Bogusław Nedoszytko

,

Małgorzata Sokołowska-Wojdyło

,

Katarzyna Ruckemann-Dziurdzińska

,

Jadwiga Roszkiewicz

,

Roman J. Nowicki