Review paper<br>Genetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris

Marta Stawczyk-Macieja; Aneta Szczerkowska-Dobosz; Krzysztof Rębała; Dorota Purzycka-Bohdan

doi:10.5114/pdia.2014.44003

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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2/2015
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abstract:

Review paper
Genetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris

Marta Stawczyk-Macieja

,

Aneta Szczerkowska-Dobosz

,

Krzysztof Rębała

,

Dorota Purzycka-Bohdan

Postep Derm Alergol 2015; XXXII, 2: 123–126

DOI: https://doi.org/10.5114/pdia.2014.44003

Online publish date: 2015/03/30

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AMA

Stawczyk-Macieja M, Szczerkowska-Dobosz A, Rębała K, Purzycka-Bohdan D. Review paperGenetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2015;32(2):123-126. doi:10.5114/pdia.2014.44003.

APA

Stawczyk-Macieja, M., Szczerkowska-Dobosz, A., Rębała, K.,  & Purzycka-Bohdan, D. (2015). Review paperGenetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 32(2), 123-126. https://doi.org/10.5114/pdia.2014.44003

Chicago

Stawczyk-Macieja, Marta, Aneta Szczerkowska-Dobosz, Krzysztof Rębała,  and Dorota Purzycka-Bohdan. 2015. "Review paperGenetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 32 (2): 123-126. doi:10.5114/pdia.2014.44003.

Harvard

Stawczyk-Macieja, M., Szczerkowska-Dobosz, A., Rębała, K.,  and Purzycka-Bohdan, D. (2015). Review paperGenetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 32(2), pp.123-126. https://doi.org/10.5114/pdia.2014.44003

MLA

Stawczyk-Macieja, Marta et al. "Review paperGenetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 32, no. 2, 2015, pp. 123-126. doi:10.5114/pdia.2014.44003.

Vancouver

Stawczyk-Macieja M, Szczerkowska-Dobosz A, Rębała K, Purzycka-Bohdan D. Review paperGenetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2015;32(2):123-126. doi:10.5114/pdia.2014.44003.

Psoriasis is a common inflammatory skin disease. It is known to be a complex condition with multifactorial mode of inheritance, however the associations between particular pathogenic pathways remain unclear. A novel report on the pathogenesis of psoriasis has recently included the genetic determination of the skin barrier dysfunction. In this paper, we focus on specific genetic variants associated with formation of the epidermal barrier and their role in the complex pathogenesis of the disease.

keywords:

Review paperGenetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris

Marta Stawczyk-Macieja , Aneta Szczerkowska-Dobosz , Krzysztof Rębała , Dorota Purzycka-Bohdan

psoriasis, epidermal differentiation complex, late cornified envelope

Review paper
Genetic background of skin barrier dysfunction in the pathogenesis of psoriasis vulgaris

Marta Stawczyk-Macieja

,

Aneta Szczerkowska-Dobosz

,

Krzysztof Rębała

,

Dorota Purzycka-Bohdan