Salvage high-dose-rate interstitial brachytherapy
for perineal recurrence of prostate cancer
after surgery and radiotherapy: a case report

Andrea Vavassori; Stefano Durante; Matteo Augugliaro; Stefania Comi; Raffaella Cambria; Federica Cattani; Roberta Lazzari; Deliu Victor Matei; Ottavio De Cobelli; Roberto Orecchia; Barbara Jereczek-Fossa

doi:10.5114/jcb.2020.100383

eISSN: 2081-2841
ISSN: 1689-832X

Journal of Contemporary Brachytherapy

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abstract:

Case report

Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report

Andrea Vavassori

¹

,

Stefano Durante

¹

,

Matteo Augugliaro

¹

,

Stefania Comi

²

,

Raffaella Cambria

²

,

Federica Cattani

²

,

Roberta Lazzari

¹

,

Deliu Victor Matei

³

,

Ottavio De Cobelli

^{3, 4}

,

Roberto Orecchia

⁵

,

Barbara Alicja Jereczek-Fossa

^{1, 4}

Department of Radiotherapy, IEO European Institute of Oncology IRCCS, Milan, Italy
Unit of Medical Physics, IEO European Institute of Oncology IRCCS, Milan, Italy
Department of Urology, IEO European Institute of Oncology IRCCS, Milan, Italy
Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
Scientific Directorate, IEO European Institute of Oncology IRCCS, Milan, Italy

J Contemp Brachytherapy 2020; 12, 5: 492–496

DOI: https://doi.org/10.5114/jcb.2020.100383

Online publish date: 2020/10/30

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AMA

Vavassori A, Durante S, Augugliaro M, et al. Salvage high-dose-rate interstitial brachytherapy
for perineal recurrence of prostate cancer
after surgery and radiotherapy: a case report. Journal of Contemporary Brachytherapy. 2020;12(5):492-496. doi:10.5114/jcb.2020.100383.

APA

Vavassori, A., Durante, S., Augugliaro, M., Comi, S., Cambria, R.,  & Cattani, F. et al. (2020). Salvage high-dose-rate interstitial brachytherapy
for perineal recurrence of prostate cancer
after surgery and radiotherapy: a case report. Journal of Contemporary Brachytherapy, 12(5), 492-496. https://doi.org/10.5114/jcb.2020.100383

Chicago

Vavassori, Andrea, Stefano Durante, Matteo Augugliaro, Stefania Comi, Raffaella Cambria, Federica Cattani,  and Roberta Lazzari et al. 2020. "Salvage high-dose-rate interstitial brachytherapy
for perineal recurrence of prostate cancer
after surgery and radiotherapy: a case report". Journal of Contemporary Brachytherapy 12 (5): 492-496. doi:10.5114/jcb.2020.100383.

Harvard

Vavassori, A., Durante, S., Augugliaro, M., Comi, S., Cambria, R., Cattani, F., Lazzari, R., Matei, D., De Cobelli, O., Orecchia, R.,  and Jereczek-Fossa, B. (2020). Salvage high-dose-rate interstitial brachytherapy
for perineal recurrence of prostate cancer
after surgery and radiotherapy: a case report. Journal of Contemporary Brachytherapy, 12(5), pp.492-496. https://doi.org/10.5114/jcb.2020.100383

MLA

Vavassori, Andrea et al. "Salvage high-dose-rate interstitial brachytherapy
for perineal recurrence of prostate cancer
after surgery and radiotherapy: a case report." Journal of Contemporary Brachytherapy, vol. 12, no. 5, 2020, pp. 492-496. doi:10.5114/jcb.2020.100383.

Vancouver

Vavassori A, Durante S, Augugliaro M, Comi S, Cambria R, Cattani F et al. Salvage high-dose-rate interstitial brachytherapy
for perineal recurrence of prostate cancer
after surgery and radiotherapy: a case report. Journal of Contemporary Brachytherapy. 2020;12(5):492-496. doi:10.5114/jcb.2020.100383.

Perineal seeding of tumor cells from prostate cancer (PCa) is very rare, and no standard treatment exists for this atypical presentation with no evidence of distant metastases. Local excision or external beam radiotherapy are used as local salvage treatments for such perineal masses, including those occurring after biopsy, surgery, or interstitial brachytherapy.

We report on a patient who presented no evidence of disease and no late urinary or gastrointestinal toxicities at 58 months after receiving high-dose-rate brachytherapy (HDR-BT) for perineal recurrence of PCa after radical prostatectomy and salvage external beam radiotherapy. To the best of our knowledge, this is the first case treated with HDR-BT in this scenario.

keywords:

Salvage high-dose-rate interstitial brachytherapy for perineal recurrence of prostate cancer after surgery and radiotherapy: a case report

Andrea Vavassori 1 , Stefano Durante 1 , Matteo Augugliaro 1 , Stefania Comi 2 , Raffaella Cambria 2 , Federica Cattani 2 , Roberta Lazzari 1 , Deliu Victor Matei 3 , Ottavio De Cobelli 3, 4 , Roberto Orecchia 5 , Barbara Alicja Jereczek-Fossa 1, 4

interstitial HDR brachytherapy, perineal prostate cancer recurrence, reirradiation

Andrea Vavassori

¹

,

Stefano Durante

¹

,

Matteo Augugliaro

¹

,

Stefania Comi

²

,

Raffaella Cambria

²

,

Federica Cattani

²

,

Roberta Lazzari

¹

,

Deliu Victor Matei

³

,

Ottavio De Cobelli

^{3, 4}

,

Roberto Orecchia

⁵

,

Barbara Alicja Jereczek-Fossa

^{1, 4}