eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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4/2007
vol. 24
 
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abstract:

Special work
The genetic diagnostics of primary cutaneous T-cell lymphomas
Part I: Application of TCR gene rearrangement analysis in diagnostics of cutaneous T-cell lymphomas

Małgorzata Sokołowska-Wojdyło
,
Bogusław Nedoszytko
,
Monika Zabłotna
,
Jolanta Gleń
,
Waldemar Placek

Post Dermatol Alergol 2007; XXIV, 4: 151–156
Online publish date: 2007/08/29
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T-cell receptor rearrangement has become a standard in diagnostics of cutaneous T-cell lympoma (CTCL). The process of somatic recombination and description of polymerase chain reaction method necessary in analysis of TCR genes monoclonality have been described in the 1st part of the trilogy consisting of genetic analysis of CTCL
keywords:

CTCL, TCR, chromosomal aberration, clone, monoclonality

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