eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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abstract:
Original paper

TCA chemical peel as facial anti-aging therapy for postmenopausal women: a randomised clinical study

Laura Piejko
1, 2
,
Małgorzata Glenc-Ambroży
3
,
Jan Juszczyk
4
,
Joanna Czajkowska
4
,
Monika Bugdol
4
,
Mikołaj Łanocha
5
,
Beata Bergler-Czop
5
,
Anna Polak
1

  1. Institute of Physiotherapy and Health Sciences, Academy of Physical Education, Katowice, Poland
  2. Clinical Psychiatric Hospital, Rybnik, Poland
  3. Amber Academy Research Center, Rybnik, Poland
  4. Faculty of Biomedical Engineering, Silesian University of Technology, Zabrze, Poland
  5. Department of Dermatology, Medical University of Silesia, Katowice, Poland
Adv Dermatol Allergol
DOI: https://doi.org/10.5114/ada.2024.144161
Online publish date: 2024/10/29
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Introduction:
A randomised controlled clinical trial involving a novel trichloroacetic acid (TCA) peel was performed. The experimental group, the placebo group, the staff administering treatments, the persons evaluating intervention results, and the statistical analyst were all blinded.

Aim:
10% as anti-aging skin therapy for postmenopausal women.

Material and methods:
Forty-six postmenopausal women at a mean age of 60.63 ±2.6 years were equally and randomly divided into an experimental group (EG; n = 23) and a control group (CG; n = 23), which received facial skin treatments with a TCA peel and a placebo solution, respectively. Treatment sessions were performed once weekly for 4 consecutive weeks. Between the sessions, the participants were required to apply the same post-peel cream in the morning and evening. Skin-aging parameters – hydration, elasticity, and sebum levels – were measured using the MC 750 B2 (Courage + Khazaka electronic GmbH, Cologne, Germany), wrinkle appearance was assessed based on photographs taken with the Fujifilm XT-1 camera, and the Wrinkle Severity Rating Scale and skin aesthetic improvement was rated using the Patient’s Aesthetic Improvement Scale and the Global Aesthetic Improvement Scale. All assessments were carried out pre- and post-intervention and at months 1 and 3 of follow-up.

Results:
Skin hydration and participants’ satisfaction with treatment results measured post-treatment and at month 3 of follow-up were greater in the EG than in the CG.

Conclusions:
The TCA chemical peel improved facial skin hydration in postmenopausal women, but not skin elasticity. The results of the treatments were rated by the participants as satisfying.

keywords:

chemical peel, skin rejuvenation, trichloroacetic acid
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