The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation

Alicja Góralczyk; Katarzyna Kolossa; Marzena Waszczak-Jeka; Rafał Adamczak; Sławomir Jeka

doi:10.5114/ada.2020.96294

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Review paper

The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation

Alicja Góralczyk

¹

,

Katarzyna Kolossa

¹

,

Marzena Waszczak-Jeka

²

,

Rafał Adamczak

³

,

Sławomir Jeka

^{1, 4}

Department of Rheumatology and Connective Tissue Diseases, University Hospital No. 2, Bydgoszcz, Poland
Medycyna Kliniczna, Warsaw, Poland
Department of Obstetrics and Gynaecology, University Hospital No. 2, Bydgoszcz, Poland
Collegium Medicum in Bydgoszcz, University of Nicolaus Copernicus in Torun, Poland

Adv Dermatol Allergol 2020; XXXVII (3): 306-312

DOI: https://doi.org/10.5114/ada.2020.96294

Online publish date: 2020/07/14

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AMA

Góralczyk A, Kolossa K, Waszczak-Jeka M, Adamczak R, Jeka S. The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2020;37(3):306-312. doi:10.5114/ada.2020.96294.

APA

Góralczyk, A., Kolossa, K., Waszczak-Jeka, M., Adamczak, R.,  & Jeka, S. (2020). The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 37(3), 306-312. https://doi.org/10.5114/ada.2020.96294

Chicago

Góralczyk, Alicja, Katarzyna Kolossa, Marzena Waszczak-Jeka, Rafał Adamczak,  and Sławomir Jeka. 2020. "The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 37 (3): 306-312. doi:10.5114/ada.2020.96294.

Harvard

Góralczyk, A., Kolossa, K., Waszczak-Jeka, M., Adamczak, R.,  and Jeka, S. (2020). The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 37(3), pp.306-312. https://doi.org/10.5114/ada.2020.96294

MLA

Góralczyk, Alicja et al. "The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 37, no. 3, 2020, pp. 306-312. doi:10.5114/ada.2020.96294.

Vancouver

Góralczyk A, Kolossa K, Waszczak-Jeka M, Adamczak R, Jeka S. The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2020;37(3):306-312. doi:10.5114/ada.2020.96294.

Chronic inflammatory diseases often affect women of childbearing age. Since biologic and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs) are more available, their use during conception, pregnancy and lactation has become a matter of concern. Current studies prove the safety of innovative therapy in pregnant women and may contribute to its wider use than before in pregnancy and lactation. It mainly concerns tumour necrosis factor a (TNF-a) inhibitors. We searched PubMed using Medical Subject Headings (MeSH) terms and identified relevant studies and guidelines. We present up-to-date knowledge of bDMARDs and tsDMARDs safety in pregnant and breastfeeding women.

keywords:

The exposure to biologic and targeted synthetic disease-modifying antirheumatic drugs in pregnancy and lactation

Alicja Góralczyk 1 , Katarzyna Kolossa 1 , Marzena Waszczak-Jeka 2 , Rafał Adamczak 3 , Sławomir Jeka 1, 4

bDMARDs, tsDMARDs, inflammatory disease, pregnancy, lactation

Alicja Góralczyk

¹

,

Katarzyna Kolossa

¹

,

Marzena Waszczak-Jeka

²

,

Rafał Adamczak

³

,

Sławomir Jeka

^{1, 4}