The relationship between severity of disease and vitamin D levels in children with atopic dermatitis

Ozlem Su; Anıl Gülsel Bahalı; Ayşegül Doğan Demir; Dilek Biyik Ozkaya; Selçuk Uzuner; Didem Dizman; Nahide Onsun

doi:10.5114/pdia.2017.66054

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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3/2017
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Original paper

The relationship between severity of disease and vitamin D levels in children with atopic dermatitis

Ozlem Su

,

Anıl Gülsel Bahalı

,

Ayşegül Doğan Demir

,

Dilek Biyik Ozkaya

,

Selçuk Uzuner

,

Didem Dizman

,

Nahide Onsun

Adv Dermatol Allergol 2017; XXXIV (3): 224-227

DOI: https://doi.org/10.5114/pdia.2017.66054

Online publish date: 2017/05/29

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AMA

Su O, Bahalı A, Demir A, et al. The relationship between severity of disease and vitamin D levels in children with atopic dermatitis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2017;34(3):224-227. doi:10.5114/pdia.2017.66054.

APA

Su, O., Bahalı, A., Demir, A., Ozkaya, D., Uzuner, S.,  & Dizman, D. et al. (2017). The relationship between severity of disease and vitamin D levels in children with atopic dermatitis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 34(3), 224-227. https://doi.org/10.5114/pdia.2017.66054

Chicago

Su, Ozlem, Anıl Gülsel Bahalı, Ayşegül Doğan Demir, Dilek Biyik Ozkaya, Selçuk Uzuner, Didem Dizman,  and Nahide Onsun. 2017. "The relationship between severity of disease and vitamin D levels in children with atopic dermatitis". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 34 (3): 224-227. doi:10.5114/pdia.2017.66054.

Harvard

Su, O., Bahalı, A., Demir, A., Ozkaya, D., Uzuner, S., Dizman, D.,  and Onsun, N. (2017). The relationship between severity of disease and vitamin D levels in children with atopic dermatitis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 34(3), pp.224-227. https://doi.org/10.5114/pdia.2017.66054

MLA

Su, Ozlem et al. "The relationship between severity of disease and vitamin D levels in children with atopic dermatitis." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 34, no. 3, 2017, pp. 224-227. doi:10.5114/pdia.2017.66054.

Vancouver

Su O, Bahalı A, Demir A, Ozkaya D, Uzuner S, Dizman D et al. The relationship between severity of disease and vitamin D levels in children with atopic dermatitis. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2017;34(3):224-227. doi:10.5114/pdia.2017.66054.

Introduction: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disorder. Vitamin D is a liposoluble vitamin synthesized mainly in the skin. Vitamin D has several effects on the skin.

Aim: To assess the serum level of vitamin D in children with AD and determine its relation to AD severity.

Material and methods: Sixty patients with AD were enrolled in the study. We evaluated disease severity using the SCORing Atopic Dermatitis (SCORAD) index. The control group consisted of 37 healthy subjects.

Results: The mean serum concentration of 25(OH)D3 in patients with AD was not statistically different from control subjects (p = 0.065). The vitamin D level was significantly lower in moderate and severe AD compared with mild AD, and this difference was statistically significant (p = 0.001 and p = 0.004). Vitamin D showed a negative correlation with serum total IgE levels (p = 0.007). There was no significant correlation between total IgE levels and SCORAD scores (p = 0.089).

Conclusions: This study suggests that a low serum vitamin D level is inversely associated with severity of AD in children. Vitamin D has not been included in the routine treatment of AD because of the conflicting results of various studies. Thus, there is a need for more detailed and prospective studies.

keywords:

The relationship between severity of disease and vitamin D levels in children with atopic dermatitis

Ozlem Su , Anıl Gülsel Bahalı , Ayşegül Doğan Demir , Dilek Biyik Ozkaya , Selçuk Uzuner , Didem Dizman , Nahide Onsun

atopic dermatitis, vitamin D, SCORing Atopic Dermatitis

Ozlem Su

,

Anıl Gülsel Bahalı

,

Ayşegül Doğan Demir

,

Dilek Biyik Ozkaya

,

Selçuk Uzuner

,

Didem Dizman

,

Nahide Onsun