eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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6/2020
vol. 37
 
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abstract:
Original paper

The role of the nasal allergen provocation test in local allergic rhinitis cases: a preliminary report

Edyta Krzych-Fałta
1
,
Konrad Furmańczyk
1, 2
,
Diana Dziewa-Dawidczyk
2
,
Oksana Wojas
1
,
Katarzyna Reklewska
1
,
Bolesław K. Samoliński
1

  1. Unit of Environmental Hazard Prevention and Allergology, Medical University of Warsaw, Warsaw, Poland
  2. Chair of Applied Mathematics, Faculty of Applied Informatics and Mathematics, Warsaw University of Life Sciences, Warsaw, Poland
Adv Dermatol Allergol 2020; XXXVII (6): 890–897
Online publish date: 2019/05/15
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Introduction
The current state of knowledge is that allergic rhinitis can occur in two forms. One is allergic rhinitis as a manifestation of a systemic allergy with systemic atopy and positive results of skin prick tests or sIgE tests. The other is local allergic rhinitis (LAR) as a local allergic reaction affecting only the nasal mucosa without systemic atopy.

Aim
To attempt to assess the usefulness of the nasal allergen provocation test for the purposes of differential diagnosis and the qualification of LAR patients for therapy.

Material and methods
The subjects in the study were a group of 6 adults diagnosed with LAR on the basis of their medical history and the results of nasal allergen provocation tests, with the allergens being house dust mites (Dermatophagoides pteronyssinus, Dermatophagoides farinae). The methods adopted in the study were a point-based rating scale as a measure of nasal/extranasal complaints and active anterior rhinomanometry.

Results
Significant differences (p < 0.05) were observed, using the subjective rating scale, in relation to registered nasal and extranasal complaints in the early phase of the allergic reaction. Similarly, the rhinomanometry method revealed significant differences in nasal resistance values before and after the administration of an allergen.

Conclusions
The nasal allergen provocation test is the only testing tool that objectively measures the degree of the patient’s allergic reactions and is useful in qualifying LAR patients for further therapy.

keywords:

local allergic reaction, nasal allergen provocation test

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