Treatment of infections caused by Herpes simplex virus type 1 and 2 and Varicella-zoster virus

Oliwia Jakubowicz; Ryszard Żaba; Magdalena Czarnecka-Operacz

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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4/2010
vol. 27

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abstract:

Treatment of infections caused by Herpes simplex virus type 1 and 2 and Varicella-zoster virus

Oliwia Jakubowicz

,

Ryszard Żaba

,

Magdalena Czarnecka-Operacz

Post Dermatol Alergol 2010; XXVII, 4: 303-307

Online publish date: 2010/09/23

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Herpes viruses, that is HSV (Herpes simplex virus) type 1 and 2 and also VZV (Varicella-zoster virus), are among the most common human pathogens whose genome consists of DNA. So far over 100 species of herpes viruses have been identified, of which at least 8 cause human infections. Several antiviral medications are available on the Polish pharmaceutical market. However, the most difficult problem is related to the group of immunocompromised patients with herpes virus infections, due to the severe course of the viral infection and frequent resistance to the available antiviral medications. This paper is a review of available updated knowledge concerning selected medications, their antiviral mechanism of action and potential adverse effects. Moreover, therapeutic schemes for infections caused by HSV-1, HSV-2 and VZV viruses as well as in immunocompetent and immunocompromised patients have been presented.

keywords:

Treatment of infections caused by Herpes simplex virus type 1 and 2 and Varicella-zoster virus

Oliwia Jakubowicz , Ryszard Żaba , Magdalena Czarnecka-Operacz

Herpesviridae, antiviral drugs, treatment

Oliwia Jakubowicz

,

Ryszard Żaba

,

Magdalena Czarnecka-Operacz