Wound healing complications in oncological patients: perspectives for cellular therapy

Milena Deptuła; Jacek Zieliński; Anna Wardowska; Michał Pikuła

doi:10.5114/ada.2018.72585

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Review paper

Wound healing complications in oncological patients: perspectives for cellular therapy

Milena Deptuła

,

Jacek Zieliński

,

Anna Wardowska

,

Michał Pikuła

Adv Dermatol Allergol 2019; XXXVI (2): 139-146

DOI: https://doi.org/10.5114/ada.2018.72585

Online publish date: 2018/01/04

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Various types of cancer are nowadays a serious medical and social problem and a great challenge for modern medicine. The majority of anticancer therapy is based on traditional chemotherapy and radiotherapy. Both of these highly non-specific types of treatment have a number of serious side effects including wound healing complications. Radiotherapy and chemotherapy mostly affect rapidly dividing skin cells (e.g. keratinocytes), as well as fibroblasts, melanocytes, endothelial and immune cells. Currently, there are many strategies to improve wound healing in oncological patients, including various types of dressings, biomaterials, growth factors, and cell therapies.

keywords:

Wound healing complications in oncological patients: perspectives for cellular therapy

Milena Deptuła , Jacek Zieliński , Anna Wardowska , Michał Pikuła

wounds, cancers, cell therapy

Milena Deptuła

,

Jacek Zieliński

,

Anna Wardowska

,

Michał Pikuła