eISSN: 2081-2841
ISSN: 1689-832X
Journal of Contemporary Brachytherapy
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3/2019
vol. 11
 
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abstract:
Original paper

Carotid dosimetry after re-irradiation with 131Cs permanent implant brachytherapy in recurrent, resected head and neck cancer

Amanda Walsh
1
,
Emily Hubley
2
,
Laura Doyle
2
,
David Cognetti
1
,
Joseph Curry
1
,
Voichita Bar-Ad
2
,
Adam Luginbuhl
1

  1. Department of Otolaryngology Head and Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA
  2. Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, USA
J Contemp Brachytherapy 2019; 11, 3: 221–226
DOI: https://doi.org/10.5114/jcb.2019.86298
Online publish date: 2019/06/28
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Purpose
Permanent seed implant cesium-131 (131Cs) brachytherapy provides highly localized radiation for patients with recurrent head and neck cancer (HNC), who may be ineligible for external beam radiation therapy due to a high-risk of toxicity. As carotid blowout is a concern in the setting of re-irradiation, a dose to the carotid artery was examined for 131Cs brachytherapy implants.

Material and methods
Eleven patients were implanted with 131Cs adjacent to carotid at the time of resection for recurrent HNC. Vascularized tissue flaps were used in some patients. The carotid artery was contoured on the post-implant brachytherapy treatment plan, and the maximum carotid point dose and minimum carotid-seed distances are reported. The incidence of carotid blowout in the follow-up period was also measured.

Results
The maximum carotid dose was 77 ±52 Gy (range, 3-158 Gy). The closest seed to the carotid artery was 0.8 ±0.8 cm (range, 0.2-2.6 cm). One patient without a flap experienced carotid blowout, which was attributed to a non-healing wound rather than to high radiation doses.

Conclusions
Carotid artery doses from 131Cs are reported. Vascularized tissue flaps should be considered when planning 131Cs brachytherapy.

keywords:

head and neck cancer, recurrent, brachytherapy, cesium-131, carotid blowout

  
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