High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report

Yoshiaki Takagawa; Naoya Murakami; Hiroshi Igaki; Hiroyuki Okamoto; Jun Itami

doi:10.5114/jcb.2022.115161

eISSN: 2081-2841
ISSN: 1689-832X

Journal of Contemporary Brachytherapy

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2/2022
vol. 14

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abstract:

Case report

High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report

Yoshiaki Takagawa

^{1, 2}

,

Naoya Murakami

²

,

Hiroshi Igaki

²

,

Hiroyuki Okamoto

³

,

Jun Itami

^{2, 4}

Department of Minimally Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan
Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan
Department of Medical Physics, National Cancer Center Hospital, Tokyo, Japan
Department of Radiation Therapy Center, Shin-Matsudo Central General Hospital, Chiba, Japan

J Contemp Brachytherapy 2022; 14, 2: 198–204

DOI: https://doi.org/10.5114/jcb.2022.115161

Online publish date: 2022/03/31

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We report on a patient with metastatic extraskeletal myxoid chondrosarcoma (EMC), who was treated with palliative high-dose-rate (HDR) interstitial brachytherapy (ISBT). The patient was an 87-year-old woman who underwent an amputation for a bulky tumor in her right ankle joint. EMC was histopathologically confirmed. She presented with a large right inguinal lymph node metastasis of EMC 16 months after surgery. Palliative HDR-ISBT (30 Gy/2 fractions in 1 day) for the right inguinal lymph node metastasis was administered to shorten treatment period. Additional HDR-ISBT (30 Gy/2 fractions in 1 day) was administered for the management of subsequent subcutaneous metastasis to the right breast and right popliteal fossa. HDR-ISBT provided significant long-term control of the recurrent tumor in all three sites, without severe acute and late toxicity. Thus, HDR-ISBT regimen of 30 Gy/2 fractions in 1 day can be a suitable option for both palliation and long-term local control for patients with metastatic EMC.

keywords:

High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report

Yoshiaki Takagawa 1, 2 , Naoya Murakami 2 , Hiroshi Igaki 2 , Hiroyuki Okamoto 3 , Jun Itami 2, 4

extraskeletal myxoid chondrosarcoma, palliation, high-dose-rate, interstitial brachytherapy

Yoshiaki Takagawa

^{1, 2}

,

Naoya Murakami

²

,

Hiroshi Igaki

²

,

Hiroyuki Okamoto

³

,

Jun Itami

^{2, 4}