The susceptibility of patients’ with psoriasis nail plates to fungal infection

Anna B. Macura; Bolesław Pawlik; Ewa Legieć-Krzemień

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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6/2004
vol. 21

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abstract:

The susceptibility of patients’ with psoriasis nail plates to fungal infection

Anna B. Macura

,

Bolesław Pawlik

,

Ewa Legieć-Krzemień

PDiA 2004; XXI, 6: 296–299

Online publish date: 2004/12/20

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The objective of the study was evaluation of the finger and toe nail fragments collected from psoriasis patients’ susceptibility to fungal infection. Toe and finger nail fragments (scrapings) collected from 34 psoriasis patients and 27 healthy volunteers were experimentally ex vivo infected with C. albicans and T. mentagrophytes strains. After incubation, the effectiveness of infection was evaluated in clarified microscopic preparations on the basis of the number of hyphe penetrating the nail fragments. The statistical analysis revealed that toenails but not fingernails of the psoriasis patients were significantly more susceptible to C. albicans infection. No significant difference was found between the susceptibility of both finger and toe nails to T. mentagrophytes infection between the psoriasis patients and the controls.

keywords:

The susceptibility of patients’ with psoriasis nail plates to fungal infection

Anna B. Macura , Bolesław Pawlik , Ewa Legieć-Krzemień

psoriasis, onychomycosis, Candida albicans, Trichophyton mentagrophytes

Anna B. Macura

,

Bolesław Pawlik

,

Ewa Legieć-Krzemień