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Rola wybranych składników odżywczych we wspomaganiu leczenia farmakologicznego choroby Alzheimera

Marietta Bracha
Alina Jaroch

Department of Geriatrics, Division of Biochemistry and Biogerontology, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland, Polska
Department of Clinical Neuropsychology, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland, Polska
Pielęgniarstwo w Opiece Długoterminowej tom 7, rok 2022, numer 4, s. 5-15
Data publikacji online: 2023/02/28
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1. Aaseth J, Alexander J, Bjørklund G, Hestad K, Dusek P, Roos PM, Alehagen U. Treatment strategies in Alzheimer’s disease: a review with focus on selenium supplementation. Biometals. 2016 Oct;29(5):827-39. doi: 10.1007/s10534-016-9959-8
2. Ahmed T, Wang CK. Black Garlic and Its Bioactive Compounds on Human Health Diseases: A Review. Molecules. 2021 Aug 19;26(16):5028.
3. An Y., Feng L., Zhang X. i wsp., Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1, Clin. Epigenetics, 2019, 11(1), 139.
4. Athanasopoulos D., Karagiannis G., Tsolaki M., Recent findings in Alzheimer disease and nutrition focusing on epigenetics, Adv. Nutr., 2016,7(5), 917–27.
5. Barberger-Gateau P., Letenneur L., Deschamps V. et al., Fish, meat and risk of dementia: cohort study, BMJ, 2002, 325, 932-933.
6. Barberger-Gateau P., Raitin C., Letenneur L., Berr C., Tzourio C., Dartigues J.F., Alperovitch A., Dietary Patterns and Risk of Dementia: The Three-City Cohort Study, Neurology, 2007, 69, 1921–1930.
7. Barczak A., Skuteczność kliniczna doustnego preparatu Souvenaid jako wsparcia niefarmakologicznego osób z choroba Alzheimera-przegląd badań, Aktualn. Neurol., 2017, 2, 115-120.
8. Bazinet R. P., Layé S. (2014). Polyunsaturated fatty acids and their metabolites in brain function and disease. Nat. Rev. Neurosci. 15 771–785.
9. Blusztajn JK, Slack BE, Mellott TJ. Neuroprotective Actions of Dietary Choline. Nutrients. 2017 Jul 28;9(8):815. doi: 10.3390/nu9080815.
10. Bondi M.W., Edmonds E.C., Salmon D.P., Alzheimer’s disease: past, present, and future, J Int Neuropsychol Soc., 2017, 23, 818–31.
11. Browne D., McGuinness B., Woodside J.V., McKay G.J., Vitamin E and Alzheimer’s disease: What do we know so far?, Clinical Interventions in Aging, 2019, 14, 1303–1317.
12. Chang CH, Chen KC, Liaw KC, Peng CC, Peng RY. Astaxanthin Protects PC12 Cells against Homocysteine- and Glutamate-Induced Neurotoxicity. Molecules. 2020 Jan 5;25(1):214. doi: 10.3390/molecules25010214.
13. Clarke, R., Birks, J., Nexo, E., Ueland, P.M., Schneede, J., Scott, J.,Molloy, A., Evans, J.G., Low vitamin B-12 status and risk of cognitive decline in older adults. Am. J. Clin. Nutr., 2007
14. Cohen B.M., Renshaw P.F., Stoll A.L., Wurtman R.J., Yurgelun-Todd D., Babb S.M., Decreased Brain Choline Uptake in Older Adults. An in Vivo Proton Magnetic Resonance Spectroscopy Study, JAMA, 1995, 274, 902–907.
15. Cohn J.S., Kamili A., Wat E., Chung r.W., Tandy S., Dietary phospholipids and intestinal cholesterol absorption, Nutrients, 2010, 2, 116-127.
16. Conquer J.A., Tierney M.C., Zecevic J.: Fatty acid analysis from blood plasma of patients with Alzheimer’s disease, other types of dementia, and cognitive impairment, Lipids, 2000, 35, 1305- 1312.
17. Costa LG, Garrick JM, Roquè PJ, Pellacani C. Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More. Oxid Med Cell Longev. 2016; https://doi. org/10.1155/2016/2986796
18. Cummings J., Scheltens P., McKeith I., Blesa R., Harrison J.E., Bertolucci P.H.F., Rockwood K., Wilkinson D.,Wijker W., Bennett D.A. et al., Effect Size Analyses of Souvenaid in Patients with Alzheimer’s Disease, J. Alzheimers Dis., 2017, 55, 1131–1139.
19. Dauncey M.J., Nutrition, the Brain and Cognitive Decline: Insights from Epigenetics, Eur. J. Clin. Nutr., 2014, 68, 1179–1185.
20. Dey A., Bhattacharya R., Mukherjee A., Pandey D.K. Natural products against Alzheimer’s disease: Pharmaco-therapeutics and biotechnological interventions. Biotechnol. Adv. 2017;35:178–216.
21. Dongsheng J. Xiaming W., Delong L., Ping L., Sitao Z., Debo G., Fei G., Mengxiao Z., Yuliang X., Protective effects of chondroitin sulphate nano-selenium on a mouse model of Alzheimer’s disease, International Journal of Biological Macromolecules, 2020, 154, 233-245.
22. Elias, M.F., Robbins, M.A., Budge, M.M., Elias, P.K., Brennan, S.L., Johnston, C., Nagy, Z., Bates, C.J., 2006. Homocysteine, folate, and vitamins B-6 and B-12 blood levels in relations levels in relations to cognitive performance: the Maine-Syracuse study. Psychosom. Med. 68, 547–554.
23. Essa M.M., Akbar M., Guillemin G. The Benefits of Natural Products for Neurodegenerative Diseases, 1 ed. Springer; Cham, Switzerland: 2016. p. 496.
24. Ferreira I, Rauter AP, Bandarra NM. Marine Sources of DHA-Rich Phospholipids with Anti- Alzheimer Effect. Marine Drugs. 2022; 20(11):662. https://doi.org/10.3390/md20110662
25. Guzman-Martinez L, Calfío C, Farias GA, Vilches C, Prieto R, Maccioni RB. New Frontiers in the Prevention, Diagnosis, and Treatment of Alzheimer’s Disease. J Alzheimers Dis. 2021;82(s1):S51-S63.
26. Gwon A.R., Park J.S., Park J.H., Baik S.H., Jeong H.J., Hyun D.H., Park K.W., Jo D.G.: Selenium attenuates Aproduction and Aβ-induced neuronal death, Neuroscience Letters, 2010, 369, 391- 395.
27. Hollenbeck CB. An introduction to the nutrition and metabolism of choline. Cent Nerv Syst Agents Med Chem. 2012 Jun;12(2):100-13. doi: 10.2174/187152412800792689.
28. Huang TL, Zandi PP, Tucker KL, Fitzpatrick AL, Kuller LH, Fried LP, Burke GL, Carlson MC. Benefits of fatty fish on dementia risk are stronger for those without APOE epsilon4. Neurology. 2005 Nov 8;65(9):1409-14. doi: 10.1212/01.wnl.0000183148.34197.2e.
29. Innis S.M,. The developing brain and dietary omega-3 fatty acids, Handbook of behavior, food and nutrition. Springer, New York, 2011, 2069–2087.
30. Kalmijn S., Launer L.J., Ott A., Witteman J.C., Hofman A., Breteler M.M., Dietary Fat Intake and the Risk of Incident Dementia in the Rotterdam Study, Ann. Neurol., 1997, 42, 776–782.
31. Kennedy B.P., Bottiglieri T., Arning E., Ziegler M.G., Hansen L.A., Masliah E., Elevated S-Adenosylhomocysteine in Alzheimer Brain: Influence on Methyltransferases and Cognitive Function, J. Neural Transm., 2004, 111, 547–567.
32. Kingsley M., Effects of phosphatidylserine supplementation on exercising humans, Sports Med., 2006, 36, 657-669.
33. Kosicek M., Hecimovic S., Phospholipids and Alzheimer’s Disease: Alterations, Mechanisms and Potential Biomarkers, Int. J. Mol. Sci., 2013, 14, 1310-1322.
34. Krajewska-Kułak E., Kędziora-Kornatowska K., Cybulski M., Waszkiewicz N., Psychogeriatria, PZWL, 2017
35. Lukiw W.J., Cui J.G., Marcheselli V.L. et al., A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease, J Clin Invest., 2005, 115, 2774–2783.
36. Ma X, Li X, Wang W, Zhang M, Yang B, Miao Z. Phosphatidylserine, inflammation, and central nervous system diseases. Front Aging Neurosci. 2022 Aug 3;14:975176. doi: 10.3389/ fnagi.2022.975176.
37. Maccioni, R.B.; Calfío, C.; González, A.; Lüttges, V. Novel Nutraceutical Compounds in Alzheimer Prevention. Biomolecules 2022, 12, 249.
38. Mangialasche F, Xu W, Kivipelto M, Costanzi E, Ercolani S, Pigliautile M, Cecchetti R, Baglioni M, Simmons A, Soininen H, Tsolaki M, Kloszewska I, Vellas B, Lovestone S, Mecocci P; AddNeuroMed Consortium. Tocopherols and tocotrienols plasma levels are associated with cognitive impairment. Neurobiol Aging. 2012 Oct;33(10):2282-90. doi: 10.1016/j. neurobiolaging.2011.11.019.
39. Marefati N, Beheshti F, Memarpour S, Bayat R, Naser Shafei M, Sadeghnia HR, Ghazavi H, Hosseini M. The effects of acetyl-11-keto-β-boswellic acid on brain cytokines and memory impairment induced by lipopolysaccharide in rats. Cytokine. 2020 Jul;131:155107. doi: 10.1016/j. cyto.2020.155107.
40. Mullan K., Cardwell C.R., McGuinness B., Woodside J.V., McKay G.J., Plasma antioxidant status in patients with Alzheimer’s disease and cognitively intact elderly: a meta-analysis of case-control studies, J. Alzheimers Dis., 2018, 62(1), 305–317.
41. Murphy MJ, Brandie F, Ebare M, Harrison M, Dow E, Bartlett WA, Craig D. Personalising laboratory medicine in the ‘real world’: Assessing clinical utility, by clinical indication, of serum total B12 and Active-B12 (holotranscobalamin) in the diagnosis of vitamin B12 deficiency. Ann Clin Biochem. 2021 Sep;58(5):445-451.
42. Nowak J.Z., Przeciwzapalne „prowygaszeniowe” pochodne wielonienasyconych kwasów tłuszczowych omega-3 i omega-6, Postępy Hig Med Dosw., 2010, 64, 115–132.
43. Obeid R, Herrmann W. Mechanisms of homocysteine neurotoxicity in neurodegenerative diseases with special reference to dementia, Febs. Lett., 2006, 580(13), 2994–3005.
44. Ogawa S., Nutritional management of older adults with cognitive decline and dementia. Geriatr. Gerontol. Int., 2014, 14 (suppl. 2), 17-22.
45. Olde Rikkert M.G., Verhey F.R., Blesa R. i wsp., Tolerability and safety of Souvenaid in patients with mild Alzheimer’s disease: results of multi-center, 24-week, open-label extension study, J. Alzheimers Dis., 2015, 44, 471–480.
46. Oliveira M, Padrão A, Ramalho A, Lobo M, Teodoro AC, Gonçalves H, Freitas A. Geospatial Analysis of Environmental Atmospheric Risk Factors in Neurodegenerative Diseases: Systematic Review. Int J Environ Res Public Health. 2020 Nov 13;17(22):8414. doi: 10.3390/ijerph17228414
47. Paez-Ribes M, González-Gualda E, Doherty GJ, Muñoz-Espín D. Targeting senescent cells in translational medicine. EMBO Mol Med. 2019 Dec;11(12):e10234. doi: 10.15252/ emmm.201810234.
48. Parchem K., Bartoszek A., Fosfolipidy oraz produkty ich hydrolizy jako żywieniowe czynniki prewencyjne w chorobach cywilizacyjnych, Postepy Hig Med Dosw., 2016, 70, 1343-1361.
49. Pillai R., Uyehara-Lock J.H., Bellinger F.P., Selenium and Selenoprotein Function in Brain Disorders, IUBMB Life, 2014, 66(4), 229-239.
50. Richter Y., Herzog Y., Lifshitz Y., Hayun r., Zchut S., The effect of soybean-derived phosphatidylserine on cognitive performance in elderly with subjective memory complaints: a pilot study, Clin. Interv. Aging, 2013, 8, 557-563.
51. Sayed AS, Gomaa IEO, Bader M, El Sayed NSED. Role of 3-Acetyl-11-Keto-Beta-Boswellic Acid in Counteracting LPS-Induced Neuroinflammation via Modulation of miRNA-155. Mol Neurobiol. 2018 Jul;55(7):5798-5808.
52. Sripanidkulchai B. Benefits of aged garlic extract on Alzheimer’s disease: Possible mechanisms of action. Exp Ther Med. 2020 Feb;19(2):1560-1564
53. Szczygieł B., Gaweł M., Ukleja M. i wsp., Rola wybranych składników odżywczych we wspomaganiu leczenia farmakologicznego choroby Alzheimera, Pol. Przegl. Neurol., 2014, 10, 38–46.
54. Van der Zwaluw NL, Brouwer-Brolsma EM, van de Rest O, van Wijngaarden JP, In ‚t Veld PH, Kourie DI, Swart KM, Enneman AW, van Dijk SC, van der Velde N, Kessels RP, Smeets PA, Kok FJ, Dhonukshe-Rutten RA, de Groot LC. Folate and Vitamin B12-Related Biomarkers in Relation to Brain Volumes. Nutrients. 2016 Dec 24;9(1):8. doi: 10.3390/nu9010008.
55. Van Wijk N., Broersen L.M., de Wilde M.C., Hageman R.J.J., Groenendijk M., Sijben J.W.C., Kamphuis P.J.G.H., Targeting Synaptic Dysfunction in Alzheimer’s Disease by Administering a Specific Nutrient Combination, J. Alzheimers Dis., 2014, 38, 459–479.
56. Tamtaji O. R., Heidari-Soureshjani R., Mirhosseini N., Kouchaki E., Bahmani F., Aghadavod E. i wsp., Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer’s disease: a randomized, double-blind, controlled trial. Clin. Nutr., 2019, 38, 2569–2575.
57. West R.L., Lee J.M., Maroun L.E., Hypomethylation of the Amyloid Precursor Protein Gene in the Brain of an Alzheimer’s Disease Patient, J. Mol. Neurosci., 1995, 6, 141–146.
58. Wood AHR, Chappell HF, Zulyniak MA. Dietary and supplemental long-chain omega-3 fatty acids as moderators of cognitive impairment and Alzheimer’s disease. Eur J Nutr. 2022 Mar;61(2):589-604.
59. Yang F, Chen G. The nutritional functions of dietary sphingomyelin and its applications in food. Front Nutr. 2022 Oct 19;9:1002574. doi: 10.3389/fnut.2022.1002574.
60. Zahorska-Markiewicz B., Małecka-Tendera E., Olszanecka-Glinianowicz M., Chudek J., Patofizjologia kliniczna, Edra Urban & Partner, Wrocław, 2017.
61. Zhang L, Xie X, Sun Y, Zhou F. Blood and CSF Homocysteine Levels in Alzheimer’s Disease: A Meta-Analysis and Meta-Regression of Case-Control Studies. Neuropsychiatr Dis Treat. 2022 Oct 17;18:2391-2403.
62. Zhu J.B., Tan C.C., Tan L., Yu J.T., State of Play in Alzheimer’s Disease Genetics, J Alzheimers Dis., 2017, 58(3), 631-659.
63. The report, Neurological disorders: Public health challenges. Dostępny w internecine: https:// www.who.int/publications/i/item/9789241563369. Dostęp: 2.12.2022.
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