Ocena jakości życia w chorobie Leśniowskiego-Crohna w grupie pacjentów leczonych biologicznie

Aim
Quality of life of patients with Crohn's disease and to analyze the frequency of complications during biological treatment.

Material and methods
The study involved 120 individuals with Crohn's disease, residents of the Lodz Voivodeship. The study was conducted at the Gastroenterology Clinic and the Gastroenterology Outpatient Clinic of the Central Clinical Hospital of the Medical University of Lodz. The research tools included the standardized SF-36v2, the MNA questionnaire, and a custom-designed questionnaire developed specifically for the study.

Results
The study involved 120 patients, half of whom (n=60) were women. One in ten patients surveyed admitted to smoking cigarettes, and one in four occasionally drank alcohol. Perianal fistulas occurred in 21.7% (n=26) of respondents, internal fistulas in 5.8% (n=7) of respondents, and anal fissures in 10.8% (n=13). Respondents perceived that the disease had a variable impact on their social relationships. The majority of respondents, 35% (n=42), rated this impact as level 3, indicating a moderate impact. Based on the results of the malnutrition rate assessment, the majority of respondents 49.2% (n=59) were classified as being at risk of malnutrition, with almost one in ten (9.2%) already experiencing malnutrition.

Conclusions
The study did not find a statistically significant relationship between the incidence of Crohn's disease and gender. Crohn's disease significantly affects the professional lives of patients. The disease had a moderate impact on the respondents' relationships and social lives. The disease had a varied impact on their intimate lives, with most respondents rating it as moderate.